What is Chai-2?
Generative models that design antibodies and miniproteins.
Who is Chai-2 best for?
Chai-2 is best for pharma and biotech teams that want a few computer-designed antibodies or binders to test in the lab.
Antibody discovery teams
It designs antibodies in formats such as mAbs, VH-VL and VHH against a chosen target, and the maker reports double-digit hit rates from about 20 designs per target.
Hard-to-reach targets
It can aim at membrane proteins, small or buried epitopes, and epitopes carrying ligands or glycans, without lab workarounds such as antigen mimetics.
Miniprotein binder design
The maker reports success rates above 50% for miniproteins, which lets a team go straight to characterisation instead of high-throughput screening.
Academic research labs
Academic and non-profit groups can register for limited non-commercial early access through the same form as companies.
How much does Chai-2 cost?
Chai-2 does not publish prices: commercial access starts with an access form and a call with Chai Discovery's team, and academics can apply for limited non-commercial early access.
Chai Discovery shows no plans or prices for Chai-2. Commercial organisations fill out the access form to book a call, and access is granted under the maker's Responsible Deployment policy, which puts work on human health first. Plans and current prices are on chaidiscovery.com.
How do readers rate Chai-2?
No one has rated Chai-2 yet. Be the first.
Sign in to rate. One rating per account.
What are the best Chai-2 alternatives?
One tool on Recaply does Chai-2's job. It is open source, so you can run it on your own server.
Questions about Chai-2
What is Chai-2?
Generative models that design antibodies and miniproteins.
Who is Chai-2 for?
Chai-2 is best for pharma and biotech teams that want a few computer-designed antibodies or binders to test in the lab.
Is Chai-2 free?
You can try Chai-2 free before paying.
Is there an open source alternative to Chai-2?
Yes. Biohub ESM is an open source tool that does the same job, so you can run your own.
What are the best Chai-2 alternatives?
The closest alternatives on Recaply are Biohub ESM.
Where can I try Chai-2?
On its official website, chaidiscovery.com.
Can academic researchers use Chai-2?
Yes, on a limited basis: Chai Discovery says Chai-2 will be open for limited non-commercial use, and academic and non-profit researchers register interest through the same access form as companies. When it grants access, Chai Discovery gives priority to work that benefits human health.
MiroThinker
Latent-Y
Eye2.ai
hAIve Mix
Boltz Lab
Hydrogen-1.0